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Overexpression of PlexA induced the hyperfasciculation of R-cell axons. A, Wild type. B, Overexpression of Sema1a in R-cell axons induced the formation of thicker R-cell axonal bundles between lamina and medulla. In medulla, R-cell axons formed large clumps. C, Overexpression of PlexA caused a similar hyperfasciculation phenotype. Scale bar, 20 μm.
