Figure 7.

Learning performances in C57BL/6 and quinone reductase 2 knock-out (QR2^−/−) mice determined using both novel object recognition and rotarod tests. A, Novel object recognition in wild-type and QR2^−/−. Exploration ratios reveal that QR2^−/− mice display preference for the novel object compared with controls (*p < 0.05, two-way ANOVA with Bonferroni's post hoc tests. n = 8). B, Learning behaviors on day 2 in the rotarod test. On day 1, no difference is detected between groups, whereas on day 2, QR2^−/− show improvement in apparent learning compared with WT (*p < 0.05, paired t test; n = 12).