Comparative performance of QR2−/− and wild-type mice in schizophrenia-, anxiety-, and depression-related behaviors. No difference was seen between QR2−/− and wild-type littermates in the magnitude of startle response using PPI (n = 12), a behavior associated with psychosis (A). Similarly, no difference was observed in the elevated plus maze test, an anxiety-like behavior (B), or in the forced swim test, a depression-associated behavior (C).