Table 1.
Quantification of different modules or groups of modules in the components of the whisker-to-barrel pathway in wild-type and reeler mice
| Wild type |
Reeler |
Two-sided t test | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Brainstem (bregma −5.30) (μm2) | |||||
| Pr5 | 448,498 | 17,666 | 461,351 | 46,968 | n.s. |
| B row barrelette (mean of B1–3) | 2419 | 252 | 2320 | 713 | n.s. |
| D row barrelette (mean of B1–3) | 2534 | 311 | 2622 | 356 | n.s. |
| Barrelette form factor | 0.77 | 0.02 | 0.76 | 0.04 | n.s. |
| Thalamus (μm2) | |||||
| VPM (rows B–D, arcs 1–3) | 100,739 | 15,656 | 110,834 | 8303 | n.s. |
| B row barreloid (mean of B1–3) | 9199 | 2028 | 10,404 | 562 | n.s. |
| D row barreloid (mean of D1–3) | 10,218 | 928 | 11,047 | 643 | n.s. |
| Barreloid form factor | 0.71 | 0.03 | 0.68 | 0.05 | n.s. |
| Cortex (μm2) | |||||
| PMBSF (rows A–E, arcs 1–3) | 906,889 | 40,092 | 1,237,480 | 151,540 | *p < 0.001 |
| B row barrel (mean of B 1–3) | 55,473 | 7478 | 52,059 | 6625 | n.s. |
| D row barrel (mean of B 1–3) | 62,390 | 8652 | 65,677 | 17,629 | n.s. |
| Barrel (mean of rows A–E and arcs 1–4) | 51,774 | 3731 | 53,373 | 8023 | n.s. |
| Septum area, one barrel (mean of rows A–E and arcs 1–3) | 8609 | 828 | 30,453 | 10,184 | *p < 0.001 |
| Barrel form factor | 0.83 | 0.02 | 0.78 | 0.04 | *p < 0.05 |
PMBSF, Posteromedial barrel subfield; n.s., not significant.