Table 2.

Absorption parameters of SA5, SA6, and DISS in the intestines of rats ($\overline{\mathbf{x}}\pm \mathrm{s}$; n = 5).

Compound	Concentration (mg/ml)	K a (μg·cm−2·min−1)	P app (×10−5cm/min)	P (%)
SA5	0.025	0.0091 ± 0.0011	0.61 ± 0.070	2.59 ± 0.23
	0.050	0.031 ± 0.0012∗∗	1.05 ± 0.039 ∗∗	4.33 ± 0.13 ∗∗
	0.075	0.033 ± 0.0014∗∗	0.73 ± 0.032 ∗,##	3.16 ± 0.07 ∗,##
SA6	0.043	0.020 ± 0.0017	0.77 ± 0.065	3.29 ± 0.25
	0.086	0.041 ± 0.0041∗∗	0.80 ± 0.079	3.64 ± 0.27
	0.130	0.048 ± 0.0040∗∗,	0.62 ± 0.52 ∗,#	2.79 ± 0.11 ∗,##
DISS	0.099	0.015 ± 0.0005	0.26 ± 0.068	1.13 ± 0.05
	0.198	0.032 ± 0.0015∗∗	0.27 ± 0.013	1.15 ± 0.04
	0.296	0.049 ± 0.022  ∗∗##,	0.28 ± 0.079	1.18 ± 0.04

^∗∗ P < 0.01 and ^∗P < 0.05, compared with low dose; ^##P < 0.01 and ^#P < 0.05, compared with medium dose.