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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Psychiatr Res. 2019 Apr 27;114:161–169. doi: 10.1016/j.jpsychires.2019.04.021

Table 2:

Summary of Results and Interpretation

Method Region Abnormal at BL Group x time interaction Correlation with PTSD symptom improvement Correlation with dissociative symptom improvement pre/post change in HC group Interpretation
ROI hippocam pus For neutral faces For neutral faces Neutral faces Decreasing activation is a potential mechanism of improvement in PTSD (re-experiencing)
ROI mid-cingulate For neutral faces For neutral faces For neutral faces Decreasing activation is a potential mechanism of improvement in PTSD (re-experiencing)
ROI amygdala For neutral faces For neutral faces For angry faces Decreasing activation is a potential mechanism of improvement in dissociation
ROI medial frontal For neutral faces For neutral faces Decreasing activation is general effect (re-experiencing and hyperarousal)
ROI lateral orbital frontal for all faces combined for happy faces Increasing activation is a potential compensatory mechanism
ROI dorsal ACC For neutral faces x angry faces
Whole brain anterior cingulate /medial frontal cluster Group x face interaction
Whole brain posterior cingulate / precuneus cluster Across all faces Across all faces Decreasing activation is a potential compensatory mechanism