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. 2010 Feb 24;30(8):3146–3155. doi: 10.1523/JNEUROSCI.4140-09.2010

Figure 3.

Figure 3.

Behavioral responses to METH, haloperidol, and SCH23390 in H-FABP KO mice. A, B, Locomotor activity of H-FABP KO mice was significantly reduced following repeated administration of 0.25 mg/kg METH (A) and 0.5 mg/kg METH (B) compared with wild-type mice. Each bar of points represents the mean ± SEM. ***p < 0.001, versus saline-treated (day 0) wild-type mice; ## p < 0.01 and ### p < 0.001, versus saline-treated (day 0) H-FABP KO mice. C, H-FABP KO mice exhibited strong haloperidol-induced catalepsy compared with wild-type mice. Each bar of points represents the mean ± SEM. **p < 0.01, versus vehicle-treated (Veh.) wild-type mice; # p < 0.05, ## p < 0.01, versus vehicle-treated (Veh.) H-FABP KO mice. § p < 0.05, §§ p < 0.01 in H-FABP KO versus wild-type mice at the same dosage. D, SCH23390-induced catalepsy did not differ significantly between wild-type and H-FABP KO mice. Each bar of points represents the mean ± SEM. *p < 0.05 and **p < 0.01 versus vehicle-treated (Veh.) wild-type mice; # p < 0.05 and ## p < 0.01 versus vehicle-treated (Veh.) H-FABP KO mice. WT, wild-type mice; KO, H-FABP KO mice.