Figure 2.

cbdnf ko mice have a markedly decrease exploratory behavior. A, Latency of first entry into the light compartment during the dark/light exploration test. B, Number of dark/light compartment transitions during the dark/light exploration test. C, Total time spent in the light chamber during the dark/light exploration test. Each wild-type (white columns) and mutant animal (black columns) was tested for a period of 6 min. All results are presented as mean ± SEM determined from the analysis of n mice per genotype (**p < 0.01, ***p < 0.001, unpaired t test).