Figure 3.

The pan-CNS BDNF deprivation unequally affects postnatal brain growth. A, Examples of a brain of a wild-type and of a cbdnf ko animal at 2 months. B, The brain wet weight of cbdnf ko mice was significantly different from wild-type mice. C, D, Volumes were determined using Nissl-stained sections of P14 and P56 hippocampi and striata from wild-type and cbdnf ko mice by Cavalieri analysis. All results are presented as mean ± SEM determined from the analysis of n mice per genotype (*p < 0.05, unpaired t test). The white bars represent wild type, and the black bars represent cbdnf ko mice.