Table 3.
Logistic regression of polymorphisms studied.
| SNP | Gene | MAF | Allele | OR (95% CI), Pdom | OR (95% CI), Padd |
|---|---|---|---|---|---|
| rs34305371 | NEGR1 | 0.02 | G | 0.92, (0.4-1.97), 0.841 | 0.88, (0.4-1.8), 0.746 |
| rs10913469 | SEC16B-RASAL2 | 0.02 | C | 1, (0.7-1.36), 0.902 | 1, (0.8-1.3), 0.826 |
| rs6548238 | TMEM18 | 0.05 | T | 0.5, (0.3-0.83), 0.008 | 0.53, (0.3-9), 0.013 |
| rs7561317 | TMEM18 | 0.06 | A | 0.52, (0.3-0.8), 0.008 | 0.5, (0.3-0.9), 0.012 |
| rs1143643 | IL-1beta | 0.25 | T | 0.93, (0.7-1.3), 0.711 | 0.88, (0.7-1.16), 0.372 |
| rs6444174 | ADIPOQ | 0.03 | C | 0.65, (0.3-1.3), 0.224 | 0.63, (0.3-1.2), 0.193 |
| rs16857402 | GNPDA2 | 0.12 | C | 1.06, (0.7-1.6), 0.743 | 1.06, (0.7-1.5), 0.745 |
| rs1800750 | TNF-alpha | 0.04 | A | 1.8, (0.9-3.6), 0.068 | 1.75, (0.9-3.3), 0.087 |
| rs1524107 | IL-6 | 0.47 | T | 0.96, (0.7-1.3), 0.847 | 0.94, (0.7-1.2), 0.670 |
| rs2069845 | IL-6 | 0.2 | G | 1.1, (0.8-1.5), 0.551 | 1.08, (0.8-1.44), 0.606 |
| rs2167270 | LEP | 0.49 | G | 0.98, (0.7-1.4), 0.916 | 0.99, (0.8-1.25), 0.990 |
| rs10838738 | MTCH2 | 0.39 | G | 1.3, (0.9-1.8), 0.126 | 1.1, (0.8-1.4), 0.379 |
| rs925946 | LGR4-LIN7C-BDNF | 0.14 | T | 0.7, (0.5-1.03), 0.072 | 0.78, (0.6-1.1), 0.128 |
| rs7138803 | BCDIN3D-FAIM2 | 0.23 | A | 1.03, (0.7-1.45), 0.825 | 1.04, (0.8-1.36), 0.775 |
| rs62033400 | FTO | 0.28 | G | 1.02, (0.7-1.5), 0.873 | 1.02, (0.7-1.3), 0.880 |
| rs11872992 | MC4R | 0.24 | A | 1.2 (0.8-1.8), 0.290 | 1.2, (0.85-1.7), 0.276 |
| rs17782313 | MC4R | 0.08 | C | 0.8, (0.5-1.3), 0.454 | 1.02, (0.6-1.6), 0.912 |
| rs29942 | KCTD15 | 0.42 | A | 0.77, (0.5-1.1), 0.158 | 0.9, (0.7-1.14), 0.402 |
OR adjusted by age, sex, and BMI. Inheritance models = dom: dominant; add: additive. MAF: minor allele frequency.