Skip to main content
. 2010 Mar 3;30(9):3508–3517. doi: 10.1523/JNEUROSCI.5386-09.2010

Figure 1.

Figure 1.

Effect of RhoB gene deletion on Rho GTPase levels and gross hippocampal morphology. A, Western blot images illustrating that the complete absence of the RhoB protein in brain tissue from RhoB−/− (−/−) mice compared with RhoB+/+ (+/+) littermates has no effect on other Rho GTPases, including Rac1 and CDC42. B, No difference in the levels of active RhoA (RhoA-GTP) or total RhoA in hippocampal tissue from RhoB−/− and RhoB +/+ littermate controls was observed. C, Comparable coronal sections (20 μm, frozen) from males were processed for Nissl staining. Note that the structures of the hippocampus are similar in both RhoB−/− and RhoB +/+ mice. Scale bar, 500 μm. Numbers represent size markers (kilodaltons).