Table 3.

Potential exosomal biomarkers of cancer metastasis.

	Potential biomarkers	Comparison analysis	Ref.
Exosomal RNAs	miR-140-3p, miR-30d-5p, miR-29b-3p, miR-130b-3p, miR-330-5p, miR-296-3p	Exosomes derived from fast- and slow-migrating groups of PDLCs	[41]
	miRNA-21 and lncRNA-ATB	Serum exosomes isolated from patients with different HCC stages	[42]
	miR-9 and miR-155	Exosomes derived from breast cells with different metastatic ability	[43]
	miR-1290 and miR-375	Plasma exosomes derived from CRPC patients with different prognosis	[44]
	miR-130b and Met	Serum exosomes isolated from prostate cancer patients and healthy donors	[45]
	circPRMT5	Serum and urine exosomes from normal people and patients with UCB	[46]
Exosomal proteins	CD82	Exosomes derived from tissue, serum, and plasma in breast cancer patients	[47]
	Eps8	Exosomes purified from human pancreatic cancer cell lines with distinct stages	[48]
	CXCR7 and CXCL12	Exosomes isolated from tissues of primary tumor, lung metastasis, and benign lung disease in CRC patients	[49]

Note: Patient-derived liver cell, PDLC; Hepatocellular carcinoma, HCC; Castration-resistant prostate cancer, CRPC; Urothelial carcinoma of the bladder, UCB; Colorectal cancer, CRC.