Table 2.
Amino Acid Sequences (Epitopes) Shared with Classical HLA-Ia Loci (HLA-A, HLA-B, HAL-Cw, and Nonclassical HLA-Ib Loci (HLA-F and HLA-G)
| HLA-E peptide sequences | No. of amino acids | HLA-I alleles | Specificity | ||||
|---|---|---|---|---|---|---|---|
| Classical Ia | Nonclassical Ib | ||||||
| A | B | Cw | F | G | |||
| 47PRAPWMEQE55 | 9 | 1 | 0 | 0 | 0 | 0 | A*3306 |
| 59EYWDRETR65 | 8 | 5 | 0 | 0 | 0 | 0 | A-restricted |
| 65RSARDTA71 (*) | 6 | 0 | 0 | 0 | 0 | 0 | E-restricted |
| 90AGSHTLQW97 | 8 | 1 | 10 | 48 | 0 | 0 | Polyspecific |
| 108RFLRGYE123 | 7 | 24 | 0 | 0 | 0 | 0 | A-restricted |
| 115QFAYDGKDY123 | 9 | 1 | 194 | 75 | 0 | 0 | Polyspecific |
| 117AYDGKDY123 | 7 | 491 | 831 | 271 | 21 | 30 | Polyspecific |
| 126LNEDLRSWTA135 | 10 | 239 | 210 | 261 | 21 | 30 | Polyspecific |
| 137DTAAQI142 | 6 | 0 | 824 | 248 | 0 | 30 | Polyspecific |
| 137DTAAQIS143 | 7 | 0 | 52 | 4 | 0 | 30 | Polyspecific |
| 143SEQKSNDASE152(*) | 10 | 0 | 0 | 0 | 0 | 0 | E-restricted |
| 157RAYLED162 | 6 | 0 | 1 | 0 | 0 | 0 | B*8201 |
| 163TCVEWL168 | 6 | 282 | 206 | 200 | 0 | 30 | Polyspecific |
| 182EPPKTHVT190 | 8 | 0 | 0 | 19 | 0 | 0 | C-restricted |
HLA-E-restricted epitopes are shown in bold italics with (*).