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. 2019 Jul 12;11:6553–6566. doi: 10.2147/CMAR.S202342

Figure 4.

Figure 4

Ezrin promotes proliferation and invasion of pancreatic cancer cells through activating Akt/mTOR pathway.

Notes: (A) The expression of Akt, p-Akt, mTOR, and p-mTOR was detected in Ezrin knockdown and overexpression cells by Western blot. β-Actin was set as the loading control. (B) The expression of Akt, mTOR, E-cadherin, and Vimentin was detected in Ezrin-overexpressed BxPC-3 cells after treatment with rapamycin or LY294002 by Western blot. β-Actin was set as the loading control. (C) Colony formation capacity was detected in Ezrin-overexpressed BxPC-3 cells after treatment with rapamycin or LY294002. (D) Invasion capacity was detected in Ezrin-overexpressed BxPC-3 cells after treatment with rapamycin or LY294002. *P<0.05, **P<0.01.