Figure 1.

Parvalbumin-immunoreactive (PV-IR) profiles in the ventral hippocampus of adult GCLM +/+ (A–D) and GCLM −/− (E–H) mice. Micrographs show horizontal sections of the entire hippocampus (A, E), and parts of CA1 (B, F), CA3 (C, G), and dendate gyrus (DG) (D, H), where PV-IR cells are clearly visible. The horizontal sections were taken ∼3.5 mm above the interaural line and −6.50 mm bregma. I–K, Stereological quantification shows that the number of PV-IR FSI (mean ± SEM) in DG and CA3 is significantly lower in GCLM −/− (n = 7) than in +/+ (n = 5) mice. In CA1, the reduced density of PV-IR FSI in GCLM −/− mice is close to significant. **p < 0.01, *p = 0.051. Scale bar: 50 μm.