Table 1.
Deficit in GSH levels in different brain structures of 35- to 40-d-old GCLM −/− relative to +/+ mice
Cortex | Hippocampus | Striatum | Midbrain | Cerebellum | |
---|---|---|---|---|---|
Percent GSH in GCLM −/− relative to +/+ mice | 36 ± 2 | 32 ± 1 | 32 ± 2 | 24 ± 2 | 26 ± 3 |
Brain total GSH deficit in GCLM −/− mice. The GSH deficit is expressed as percent of GSH levels in GCLM −/− mice relative to those in +/+ mice. GSH measurements have been performed in at least four mice per genotype and per age. Data are presented by mean ± SEM.