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. 2010 Aug 4;30(31):10391–10406. doi: 10.1523/JNEUROSCI.0381-10.2010

Figure 6.

Figure 6.

Cep120 silencing increases centrosome motility in multipolar cells. A, Time-lapse imaging of a multipolar control cell from the IZ. B, Transfection with Cep120 shRNA increases centrosome motility (red arrowheads), and the frequent extension and retraction of neurites (white arrowheads: neurite extension) (supplemental Video 2, available at www.jneurosci.org as supplemental material). C, Centrosome trajectories in control and Cep120 downregulated cells (4 h time lapse). D, Time-lapse imaging of a multipolar cell from the IZ expressing pNeuroD GFP-mir30 Cep120 shRNA. Neuronal-specific Cep120 silencing increases centrosome motility (red arrowheads). Supplemental Video 2 (available at www.jneurosci.org as supplemental material) corresponds to A, B. Time: minutes. Scale bars, 10 μm.