Figure 4.
Neurogenesis of catecholaminergic neurons is affected in Notch signaling defective mind bomb mutants. A–J, Comparison of th expression in wild-type (wt) and mind bomb (mibta52b) mutants at the indicated developmental stages. Abbreviations: AAC, arch-associated neurons; DC, diencephalic dopaminergic cluster; LC, locus coeruleus; MO, medulla oblongata; Pr, pretectal cluster; sym, sympathetic neurons; TC, telencephalic cluster; 1–6: diencephalic DA clusters DC1–DC6 (see text). A–D, G, H, Lateral views. E, F, I, J, Dorsal views. Shown are minimum intensity z-projection of transmitted light image stacks to reveal all CA groups in a single image, anterior left. Scale bars, 100 μm.