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. 2018 Sep 4;132(19):2016–2025. doi: 10.1182/blood-2018-07-859769

Table 1.

PB clonoSEQ MRD results

Subject Age at diagnosis, y MIPI risk Best response PFS, mo MRD assay time point
Time on study, mo Maintenance regimen MRD result MRD interpretation
1 51 Low CR 69+ 51 LR <10−6 Undetectable
2 55 Intermediate CR 65+ 49 LR <10−6 Undetectable
3 53 Low CR 65+ 51 LR <10−6 Undetectable
4 65 Intermediate CR 62+ 42 None* <10−6 Undetectable
5 66 High CR 62+ 62 R 3.0 × 10−6 Detectable
6 73 High PR 61+ 46 R 1.2 × 10−5 Detectable
7 56 Intermediate CR 56+ 43 None* <10−6 Undetectable
8 80 High CR 53+ 35 R <10−6 Undetectable
9 60 Low CR 45+ 42 R <10−6 Undetectable
10 82 High CR 46+ 46 R <10−6 Undetectable

R, rituximab.

*

Two subjects opted to discontinue study treatment after 3 years.