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Prior to NEBD, the LINC complex promotes the accumulation of acto-myosin to the cytoplasmic side of the nuclear envelope (i, ii). Upon NEBD, myosin II promotes contraction of the acto-myosin network on the NE remnant, thus reducing the CSV (iii). Constraining chromosomes from scattering results in efficient chromosome interaction with the spindle MTs and timely chromosome congression (iii, iv).
