Table 2.
Unadjusted odds ratios (95% CI) for logistic regression model predicting poor glycaemic control (HbA1c ≥ 80 mmol/mol, 9.5%) within insulin regimens in children with Type 1 diabetes
| Regimen | ||||||
|---|---|---|---|---|---|---|
| Insulin pump N=694 (198 events*) | Basal-bolus injections N=188 (85 events*) | Mixed insulin N= 213 (109 events*) | ||||
| Factor | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P |
| Diabetes duration, years† | 1.1 (1.01, 1.22) | 0.0265 | 1.1 (0.93, 1.26) | 0.3162 | 1.1 (0.96, 1.33) | 0.1321 |
| Non-white race/ethnicity (referent: non-Hispanic white) | 2.7 (1.74, 4.12) | <0.0001 | 1.9 (1.04, 3.42) | 0.0380 | 1.8 (1.02, 3.04) | 0.0424 |
| Female sex (referent: male) | 1.2 (0.85, 1.64) | 0.3237 | 0.8 (0.46, 1.46) | 0.4927 | 1.7 (1.00, 2.97) | 0.0495 |
| Age at cohort study visit† | 1.2 (1.07, 1.25) | 0.0003 | 1.1 (0.92, 1.20) | 0.4485 | 1.1 (0.99, 1.27) | 0.0668 |
| Number of households lived in ≥ 2 (referent: living in 1 household) | 2.4 (1.55, 3.66) | <0.0001 | 2.6 (1.26, 5.29) | 0.0093 | 3.9 (1.50, 10.10 | 0.0051 |
| Medicaid/Medicare Insurance (Referent: private insurance) | 2.6 (1.69, 3.88) | <0.0001 | 1.5 (0.80, 2.82) | 0.2087 | 2.2 (0.25, 3.87) | 0.0063 |
| Number of times missed insulin | <0.0001 | 0.0082 | 0.0011 | |||
| 1–5/week vs <1 week | 4.2 (2.75, 6.36) | <0.0001 | 2.8 (1.16, 6.80) | 0.0218 | 1.7 (0.75, 3.83) | 0.2034 |
| 1+/day vs <1 week | 3.5 (2.08, 5.96) | <0.0001 | 3.4 (1.23, 9.55) | 0.0185 | 9.8 (2.81, 33.91 | 0.0003 |
| Family conflict survey (parent report)‡ | 1.14 (1.10, 1.19) | <0.0001 | 1.2 (1.08, 1.23) | <0.0001 | 1.1 (1.06, 1.18) | <0.0001 |
| Low blood sugar survey (parent report)‡ | 0.99 (0.98, 1.00) | 0.0943 | 0.98 (0.96, 0.997) | 0.0269 | 1.00 (0.98, 1.02 | 0.8168 |
| Eating problem survey‡ | 1.06 (1.04, 1.07) | <0.0001 | 1.10 (1.05, 1.14) | <0.0001 | 1.06 (1.03, 1.08 | <0.0001 |
| Problems receiving care (access barrier; referent: no problem receiving care) | 1.1 (0.48, 2.38) | 0.8635 | 1.2 (0.35, 4.45) | 0.7375 | 0.6 (0.24, 1.55) | 0.2974 |
| Problem not spending enough time with provider (process barrier; referent: no problem spending enough time with provider) | 1.5 (1.06, 2.18) | 0.0235 | 2.0 (1.05, 3.72) | 0.0359 | 2.1 (1.13, 3.81) | 0.0183 |
OR, odds ratio.
*
Logistic regression model predicts odds of poor control, therefore events refers to number of participants with poor glycaemic control.
†
Per 1 year increase
‡
Per 1 unit increase on survey.