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. 2019 Jul 10;74(2):295–304. doi: 10.1161/HYPERTENSIONAHA.119.12956

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© 2019 The Authors.

Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 2. — Diffusion tensor magnetic resonance imaging post-processing and diffusion metrics. A, Endocardial and epicardial borders were traced manually in multiple short axis slices per heart, and subendocardium (Endo) and subepicardium (Epi) were defined as regions of interest. Subsequently, 3-dimensional volumes were rendered by tomographic reconstruction allowing analyses of both regions for the whole left ventricle (LV) or within myocardial segments (base/mid/apex). B, Representative color maps for mean diffusivity (MD) in a reconstructed cardiac long axis and different myocardial short axis segments. C, Analysis of MD. D, Analysis of fractional anisotropy (FA). Medians and quartiles with minimum and maximum values; n=9–11 per group; Student t test. *P<0.05. ISO indicates isoproterenol.