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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Neurotoxicology. 2019 Apr 3;73:161–167. doi: 10.1016/j.neuro.2019.04.002

Figure 1.

Figure 1.

Effects of i.p. THC (filled squares), CP55,940 (filled circles), AB-CHMINACA (unfilled squares), and AMB-FUBINACA (unfilled circles) on percentage of responses that occurred on the THC-associated aperture in male (panel A) and female (panel B) C57/Bl6J mice trained to discriminate 5.6 mg/kg THC (i.p.) from vehicle. Response rates for male (panel C) and female (panel D) mice for each dose are also shown. Points (filled diamonds) at the left side of each panel represent results of control tests with injected (i.p.) vehicle (V) and 5.6 mg/kg THC (T). Each point represents the mean (± SEM) of data for 12–13 male mice (panels A and C) or 12–14 female mice (panels B and D). Pound sign (#) indicates significant main effect of sex (p<0.05). Dollar sign ($) indicates significant main effect of dose or concentration (p<0.05) compared to overall vehicle condition. Asterisk (*) indicates significant interaction term and post hoc difference (p<0.05) compared to respective vehicle. Caret (^) indicates significant interaction term and post hoc difference (p<0.05) compared to other sex at indicated dose.