Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of this study. Hydroxylated ceramide-containing GD3 does not form clusters on the cell surface, leading to nonbinding of Siglec-7, and confers cells with higher sensitivity to NK cell killing. However, regular ceramide-containing GD3 forms clusters in lipid/rafts, leading to binding of Siglec-7, and makes cells less sensitive to NK activity.
