FIG 6.

Hfq generally regulates the processing of Hfq-bound sRNAs. (A) Secondary structure of the Y. pestis GlmZ sRNA. The position of the orange arrow represents the processing sites by RNase E. The black scissor represents the reported processing site from E. coli. (B) Secondary structure of the ArcZ sRNA and the two parts after processing. The position of the orange arrow represents the processing sites by RNase E. ArcZ Part1 and ArcZ Part2 represent the secondary structure after processing. (C to F) Distribution of sequencing reads (top panels) and 5′-end site density (bottom panels) of four sRNAs. Northern blot results were also shown in the figure. The orange arrow points to the RNase E cleavage sites, corresponding to the shift site of Hfq-binding peaks. GcvB and Ffs show no processing sites.