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. 2019 Jul 9;10:690. doi: 10.3389/fphar.2019.00690

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Copyright © 2019 Wei, Zhang, Zhu, Zheng, Yan, Pan, Wang, Li, Wang, Meng, Zheng, Yan, Zhai, Lu and Yuan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nobiletin suppresses the proliferation of renal cancer cells. ACHN (A) and Caki-2 (B) renal carcinoma cells were treated with different concentrations of nobiletin for 24 h, and then the inhibition rates were examined. ACHN (C) and Caki-2 (D) cells were treated with different concentrations of nobiletin for 12, 24, and 48 h, and then the inhibition rates were examined. Colony-formation assay of ACHN cells (E) and the number of colonies are shown in the graph (F). Colony-formation assay of Caki-2 cells (G) and the number of colonies are shown in the graph (H). Data are presented as means ± SD. *P < 0.05, **P < 0.01, as compared to control.