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Nobiletin inhibits the migration and invasiveness of renal cancer cells. ACHN (A) and Caki-2 (C) cells were wounded and then treated with or without nobiletin for 24 h. Images were taken at 0 and 24 h (×100 magnification). The migration distance of ACHN (B) and Caki-2 (D) cells is shown in the graph. Invasion by ACHN (E) and Caki-2 (G) cells after 24 h. The number of invasive cells is shown (F–H). Data are presented as means ± SD. *P < 0.05, **P < 0.01, as compared to control.
