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. 2019 Jul 10;10:1595. doi: 10.3389/fmicb.2019.01595

FIGURE 2.

FIGURE 2

Intraperitoneal injection of cecropin A alleviated DSS-induced IBD in C57BL6 mice. (A) the experimental design, (B) body weight changes, (C) diarrhea scores, (D) bleeding scores, and (E) DAI scores. C: the control group; Genta: the mice were pretreated by 2.5% DSS for 5 days and then received intraperitoneal injection of 5 mg/kg body weight gentamicin. Cecropin A: the mice were pretreated by 2.5% DSS for 5 days and then received intraperitoneal injection of 15 mg/kg body weight cecropin A. DSS: the mice were treated by 2.5% DSS. The control group and DSS group received intraperitoneal injection of saline. The mice were sacrificed at 8 days. The data are mean ± SEM and analyzed by one-way ANOVA (n = 9). *P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.