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. 2019 Jul 10;10:1595. doi: 10.3389/fmicb.2019.01595

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Copyright © 2019 Zhai, Zhang, Cao, Ni, Xin, Deng, Wu, Ren, Yin and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of cecropin A and gentamicin on the colon length, intestinal histological morphology and TJ protein abundances in DSS-treated mice. (A,B) the colon length, n = 9; (C) intestinal morphology, n = 5; (D,E) TJ protein abundances, n = 3. C: the control group; Genta: the mice were pretreated by 2.5% DSS for 5 days and then received intraperitoneal injection of 5 mg/kg body weight gentamicin. Cecropin A: the mice were pretreated by 2.5% DSS for 5 days and then received intraperitoneal injection of 15 mg/kg body weight cecropin A. DSS: the mice were treated by 2.5% DSS. The control group and DSS group received intraperitoneal injection of saline. The data are mean ± SEM and analyzed by one-way ANOVA. ^*P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001.