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. 2019 Jul 10;10:1595. doi: 10.3389/fmicb.2019.01595

FIGURE 5.

FIGURE 5

Effects of different treatment on gut microbiota in mice. (A,B) the relative abundance of gut microbiota in phylum and genus level. (C) LDA score, an LDA score higher than 4 was considered to be an important contributor to the model; (D) LEfSe taxonomic cladogram, different colors suggest enrichment of certain taxa in the control group (C, red), DSS group (DSS, blue), cecropin A group (green) and gentamicin group (Genta, purple); (E) the correlation analysis among gut microbiota and inflammatory cytokines. The size of the circles is based on relative abundance. C: the control group (n = 8); DSS: the mice were treated by 2.5% DSS (n = 7); cecropin A: the mice were pretreated by 2.5% DSS for 5 days and then were intraperitoneal injected by 15 mg/kg body weight cecropin A (n = 9); Genta: the mice were pretreated by 2.5% DSS for 5 days and then were intraperitoneal injected by 5 mg/kg body weight gentamicin (n = 8). The control group and DSS group were intraperitoneal injected by physiological saline. The correlation analysis was conducted by using Spearman analysis.