Table 2.
Frequency of Self‐Perceived and Objective Cancer‐Related Cognitive Impairment
| No. (%) of Patientsa | |||
|---|---|---|---|
| T2‐T1 | T3‐T1 | Overall | |
| Self‐perceived cognitive function, FACT‐Cog Domainsb | (n=80) | (n=79) | (n=79) |
| Total FACT‐Cog score | 11 (13.8) | 17 (21.5) | 22 (27.8) |
| Mental acuity | 11 (13.8) | 15 (19.0) | 19 (24.1) |
| Concentration | 10 (12.5) | 12 (15.2) | 17 (21.5) |
| Memory | 6 (7.5) | 9 (11.4) | 11 (13.9) |
| Verbal fluency | 5 (6.3) | 7 (8.9) | 10 (12.7) |
| Functional Interference | 4 (5.0) | 7 (8.9) | 11 (13.9) |
| Multitasking | 12 (15.0) | 15 (19.0) | 21 (26.6) |
| Objective cognitive function, Headminder domainsc | (n=78) | (n=78) | (n=71) |
| Processing speed | 2 (2.6) | 4 (5.2) | 5 (7.0) |
| Response speed | 2 (2.6) | 2 (2.6) | 4 (5.6) |
| Memory | 7 (9.0) | 13 (16.7) | 15 (21.1) |
| Attention | 8 (6.0) | 4 (5.2) | 9 (12.7) |
FACT‐Cog = Functional Assessment of Cancer Therapy–Cognitive Function.
a
Patients were excluded from the analysis for a particular domain if they had missing measures at T1 and/or the measured time point (T2 or T3, respectively).
b
Self‐perceived cognitive impairment was defined as any decrease in FACT‐Cog global score of 10.6 points or more, whereas self‐perceived cognitive impairment in specific domains was defined as any 15% decrease from baseline scores.
c
Objective cognitive impairment was defined as a reliable change index score < −1.5 compared with baseline in the particular Headminder domain.