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Human primary T cells transduced by CD19 chimeric antigen receptor (CAR) are able to kill CD19+ human lymphoma cell lines. (A) The transduction efficiency of T cells was measured by fluorescence-activated cell sorting (FACS) analysis as described in Materials and Methods. Two independent experiment results are presented here. (B) The sensitivity of CD19+ NHL lines (Ramos and Raji) to CD19 CAR-T cells at different E:T ratios.
Abbreviation: NHL, non-Hodgkin’s lymphoma.
