Table 2.

Summary of univariate and multivariate Cox regression analysis of OS duration in all ccRCCs

Variables	Univariate analysis			Multivariate analysis
	HR	(95% CI)	p*	HR	(95% CI)	p*
CDK5 expression (low vs high)	0.486	0.214–1.104	0.085
p21 expression (Low vs High)	0.375	0.142–0.985	0.047	0.369	0.162–0.839	0.078
CDK5/p21expression (CLPL vs Other)	0.310	0.143–0.672	0.003	0.229	0.102–0.515	< 0.001
Age (< 55 vs > 55)	1.047	1.011–1.084	0.010	1.022	0.986–1.060	0.237
TNM stage (I + II vs III + IV)	6.972	2.935–16.563	< 0.001	2.920	1.129–7.556	0.027
Fuhrman grade (I + II vs III + IV)	5.043	2.359–10.781	0.001	3.299	0.776–6.254	0.138
Tumor size (< 4 vs > 4)	4.247	1.721–10.479	0.002	3.490	1.329–9.164	0.011

CLPL CDK5 low/p21 low, HR hazard ratio, 95% CI 95% confidence interval