Table 2.
Hemodynamic characteristics of AS patients with and without concomitant T2DM
| Characteristic | T2DM n = 50 |
No diabetes n = 80 |
p value |
|---|---|---|---|
| Aortic valve area index (cm2/m2) | 0.50 ± 0.17 | 0.52 ± 0.16 | n.s. |
| Mean aortic pressure gradient (mm Hg) | 41 ± 24 | 40 ± 21 | n.s. |
| LV end-diastolic diameter (cm) | 5.1 ± 0.9 | 5.1 ± 1.0 | n.s. |
| LV mass index (g/m2) | 143 ± 41 | 152 ± 62 | n.s. |
| LV ejection fraction (%) | 51 ± 14 | 54 ± 13 | n.s. |
| LV midwall fractional shortening (%) | 11.9 ± 3.9 | 14.1 ± 3.7 | 0.001 |
| Low LV midwall fractional shortening, n (%) | 39 (78%) | 48 (60%) | 0.03 |
| Stroke volume index (mL/m2) | 33 ± 10 | 38 ± 12 | 0.01 |
| cESS (hPa) | 247 ± 105 | 209 ± 84 | 0.025 |
| Zva (mm Hg per mL/m2) | 5.8 ± 2.2 | 5.1 ± 1.8 | 0.04 |
| Pulse pressure (mm Hg) | 63 ± 14 | 64 ± 17 | n.s. |
| Systemic arterial compliance (mL/m2 per mm Hg) | 0.53 ± 0.16 | 0.62 ± 0.22 | 0.01 |
Data are shown as mean ± SD
cESS circumferential end-systolic LV midwall stress, LV left ventricular, Zva valvulo-arterial impedance