Table 10.
Comparison of correlated targets between miRCancerdb and miRFA on protein expression level
| miRCancerdb | miRFA | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Input | Cor protein | KEGG genes | Percentage (%) | Gene names | Input | Cor protein | KEGG genes | Percentage (%) | Gene names |
| hsa-mir-144 | 5 | 0 | 0 | NA | hsa-miR-144-3p | 0 | NA | NA | NA |
| hsa-mir-106b | 3 | 2 | 67 | AKT1/2/3, RB1 | hsa-miR-106b-5p | 0 | NA | NA | NA |
| hsa-mir-101 | 0 | NA | NA | NA | hsa-miR-101-3p | 5 | 1 | 20 | MTOR |
| hsa-mir-885 | 0 | NA | NA | NA | hsa-miR-885-5p | 6 | 2 | 33 | EGFR, RAD51 |
| hsa-mir-130b | 3 | 1 | 33 | SMAD4 | hsa-miR-130b-3p | 0 | NA | NA | NA |
| hsa-mir-34a | 2 | 1 | 50 | SMAD4 | hsa-miR-34a-5p | 4 | 0 | 0 | NA |
| hsa-mir-24 | 0 | NA | NA | NA | hsa-miR-24-3p | 16 | 1 | 6 | EGFR |
| hsa-mir-22 | 3 | 2 | 67 | AKT1/2/3, CDKN1A | hsa-miR-22-5p | 10 | 1 | 10 | PIK3CA |
| hsa-let-7d | 4 | 3 | 75 | AKT1/2/3, CDKN1A, RB1 | hsa-let-7d-3p | 0 | NA | NA | NA |
| hsa-mir-122 | 0 | NA | NA | NA | hsa-miR-122-5p | 2 | 0 | 0 | NA |
Cor protein = number of correlated miRNA – targets on mRNA level, KEGG genes = number of genes associated to KEGG pathway hsa05212 pancreatic cancer, percentage = percentage of KEGG genes compared to total number of correlated targets, NA = not available