Table 3.

GO analysis of DE mRNA

Term	Domain	Count	P value	Corrected P value
Single-organism process	Biological process	719	5.62E−147	3.50E−143
Single-organism cellular process	Biological process	667	2.68E−134	8.34E−131
Cellular process	Biological process	744	1.41E−129	2.93E−126
Biological regulation	Biological process	611	2.08E−105	3.24E−102
Response to stimulus	Biological process	512	9.72E−103	1.21E−99
Regulation of biological process	Biological process	584	6.30E−100	6.54E−97
Regulation of cellular process	Biological process	560	5.33E−95	4.74E−92
Cellular response to stimulus	Biological process	433	1.45E−83	1.13E−80
Positive regulation of biological process	Biological process	357	1.96E−75	1.35E−72
Single-multicellular organism process	Biological process	382	1.30E−73	8.13E−71
Cell	Cellular component	766	2.11E−125	1.22E−122
Cell part	Cellular component	764	1.94E−124	5.61E−122
Intracellular	Cellular component	659	2.32E−90	4.48E−88
Intracellular part	Cellular component	644	3.61E−87	5.23E−85
Cytoplasm	Cellular component	547	4.42E−80	5.11E−78
Organelle	Cellular component	609	3.54E−79	3.41E−77
Membrane-bounded organelle	Cellular component	565	1.51E−69	1.25E−67
Intracellular organelle	Cellular component	549	1.17E−63	8.48E−62
Extracellular region	Cellular component	301	1.98E−58	1.27E−56
Intracellular membrane-bounded organelle	Cellular component	499	2.71E−54	1.57E−52
Binding	Molecular function	688	3.91E−105	4.12E−102
Protein binding	Molecular function	563	3.38E−86	1.78E−83
Receptor binding	Molecular function	122	1.25E−29	4.38E−27
Catalytic activity	Molecular function	273	7.99E−28	2.10E−25
Carbohydrate derivative binding	Molecular function	144	2.98E−25	6.27E−23
Cytokine activity	Molecular function	44	9.25E−24	1.62E−21
Organic cyclic compound binding	Molecular function	257	1.80E−20	2.70E−18
Heterocyclic compound binding	Molecular function	249	8.28E−19	1.09E−16
Protein dimerization activity	Molecular function	86	3.02E−18	3.53E−16
Protein heterodimerization activity	Molecular function	50	2.05E−16	2.16E−14