Fig. 3.

Comparison of SRS sub-scales and CBCL/ABCL DSM-oriented sub-scales between 3q29Del and controls. a Profile of individuals with 3q29Del (n = 48) and controls (n = 59) across SRS sub-scales, showing moderate to severe impairment of 3q29Del participants in all domains except Social Motivation (RRB, Restricted Interests and Repetitive Behaviors; SCI, Social Communication and Interaction). b Profile of 3q29Del males (n = 26) and females (n = 22) and controls (n = 59) across SRS sub-scales, showing that 3q29Del males and females both score significantly higher than controls and that there are no significant differences in score between males and females. c Profile of 3q29Del participants reporting an ASD diagnosis (n = 17) and participants not reporting an ASD diagnosis (n = 31) and controls (n = 59) across SRS sub-scales, showing that 3q29Del participants score significantly higher than controls irrespective of ASD status, with 3q29Del participants reporting an ASD diagnosis scoring significantly higher than those not reporting an ASD diagnosis. d Profile of 3q29Del participants (n = 48) and controls (n = 57) across 3 DSM-oriented sub-scales from the CBCL and ABCL, showing significantly increased pathology in 3q29Del participants in all 3 domains. ***p < 0.001