Table 1.
The baseline demographics, clinical characteristics and biochemical variables between the two groups
| Variables | SVD (N = 106) | Control (N = 115) | P |
|---|---|---|---|
| Demographics | |||
| Age (Y) | 61.6 ± 13.2 | 60.5 ± 11.7 | 0.516 |
| Sex (Male, %) | 80(75.5%) | 54(47%) | 0.001* |
| Systolic blood pressure | 151.5 ± 21 | 133.7 ± 17.3 | 0.001* |
| Diastolic blood pressure | 87 ± 14.2 | 80.1 ± 12.3 | 0.001* |
| Risk factors | |||
| Hypertension | 66(62.3%) | 75(65.2%) | 0.648 |
| Diabetes mellitus | 33(31.1%) | 26(22.6%) | 0.152 |
| Coronary disease | 11(10.4%) | 16(13.9%) | 0.423 |
| Prior stroke | 26(24.5%) | 5(4.3%) | 0.001* |
| Hyperlipidaemia | 79(74.5) | 31(27%) | 0.001* |
| Atrial fibrillation | 2(2.3%) | 2(6.7%) | 0.251 |
| Peripheral arterial disease | 6(5.7%) | 3(2.6%) | 0.252 |
| Smoking | 60(56.6%) | 45(39.1%) | 0.010* |
| Blood tests | |||
| White blood cell (109/L) | 7.1 ± 2.1 | 6.9 ± 2.1 | 0.514 |
| Red blood cell (1012/L) | 4.6 ± 0.6 | 4.6 ± 0.6 | 0.773 |
| Platelet (109/L) | 210.8 ± 92.6 | 221.7 ± 55.7 | 0.290 |
| Total cholesterol (mmol/L) | 4.4 ± 0.9 | 4.3 ± 0.8 | 0.259 |
| Low-density lipoprotein (mmol/L) | 2.7 ± 0.8 | 2.4 ± 0.8 | 0.003* |
| High-density lipoprotein (mmol/L) | 1.1 ± 0.3 | 1.1 ± 0.3 | 0.103 |
| Uric acid(μmol/L) | 329.8 ± 87.9 | 330.3 ± 95.9 | 0.972 |
| Homocysteine(μmol/L) | 18.9 ± 10.5 | 18 ± 12.3 | 0.610 |
| Fasting blood glucose (mmol/L) | 5.9 ± 1.8 | 5.6 ± 1.3 | 0.231 |
| Hemoglobin A1c (%) | 6.4 ± 1.4 | 6.3 ± 1.2 | 0.737 |
| Glycated albumin(%) | 13.8 ± 2.4 | 17.5 ± 3.8 | 0.060 |
| Fibrinogen(mg/dl) | 268.5 ± 82.2 | 271.8 ± 87.3 | 0.843 |
| C-reactive protein (mg/L) | 2.05(1.2~4.0) | 2.25(0.89~4.56) | 0.925 |
| 25-hydroxy vitamin D (ng/mL) | 10.2 ± 5.6 | 14.6 ± 7.5 | 0.001* |
| Albumin (g/L) | 42.1 ± 4.4 | 42.5 ± 4.8 | 0.681 |
Values represent number (percent) for categorical variables and mean ± SD or median (interquartile range) for continuous variables. *P < 0.05 is statistically significant