Figure 7.

The morphology of the collagen hydrogel with embedded human dermal fibroblasts migrated from the non-coated membrane (A) and from the fibrin-coated membrane (B) for 14 days. The control collagen hydrogel without cells incubated at 37°C, 5% CO₂ for 14 days (C). The measurement principle for hydrogel shrinkage (D): the diameter of the hydrogel circle was measured on the gel contour marked with several points. The value of the diameter (Ø) of each hydrogel is displayed inside the hydrogel image, and is presented as mean ± standard deviation.