Table V.
Adverse reactions among 72 patients with advanced non-small cell lung cancer and epidermal growth factor receptor mutations.
| Adverse reaction | Exon 19 deletions (n=37) | An exon 21 mutation (n=35) | χ2 | P-value |
|---|---|---|---|---|
| Rash | 18 (48.6) | 17 (48.6) | <0.001 | 0.995 |
| Degree III | 1 | 1 | ||
| Degree IV | 0 | 0 | ||
| Diarrhea | 10 (27.0) | 9 (25.7) | 0.016 | 0.899 |
| Degree III | 0 | 1 | ||
| Degree IV | 0 | 0 | ||
| Nausea | 4 (10.8) | 4 (11.4) | 0.007 | 0.934 |
| Degree III | 0 | 0 | ||
| Degree IV | 0 | 0 | ||
| Vomiting | 2 (5.4) | 1 (2.9) | 0.292 | 0.589 |
| Degree III | 0 | 0 | ||
| Degree IV | 0 | 0 | ||
| Fatigue | 2 (5.4) | 2 (5.7) | 0.003 | 0.954 |
| Degree III | 0 | 0 | ||
| Degree IV | 0 | 0 | ||
| Cough | 1 (2.7) | 2 (5.7) | 0.049 | 0.523 |
| Stomatitis | 2 (5.4) | 1 (2.9) | 0.292 | 0.589 |
| Anorexia | 9 (24.3) | 10 (28.6) | 0.167 | 0.683 |
| Interstitial pneumonia | 0 | 0 |
Data are presented as n or n (%).