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. 2019 Aug;370(2):206–217. doi: 10.1124/jpet.119.258954

Fig. 2.

Fig. 2.

Effects of Dusp5 KO on renal hemodynamics. (A) Comparison of the changes in the diameter of isolated perfused Af-arts of 10-week-old normotensive rats in response to an increase in perfusion pressure from 60 to 120 mm Hg before and after removal of calcium from the bath. (B) Comparison of the myogenic response of isolated renal IAs of 24-week-old normotensive and DOCA-salt hypertensive rats in response to an increase in perfusion pressure from 60 to 180 mm Hg. (C) Comparison of autoregulation of RBF in 24-week-old normotensive and hypertensive rats. Mean values ± S.E.M. are presented. Numbers in parentheses indicate the number of animals studied per group. *P < 0.05 from the corresponding value in Dusp5 KO vs. WT rats. #P < 0.05 from DOCA-salt treated vs. baseline value within strain.