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. 2019 Aug;370(2):206–217. doi: 10.1124/jpet.119.258954

Fig. 4.

Fig. 4.

Effect of Dusp5 KO on the development of hypertension and proteinuria. The time courses of changes in MAP (A) and proteinuria (B) after the induction of DOCA-salt hypertension in WT and Dusp5 KO rats. (C) Comparison of plasma creatinine concentration after the induction of DOCA-salt hypertension in WT and Dusp5 KO rats (n = 8 rats in each group). Mean values ± S.E.M. are presented. Numbers in parentheses indicate the number of animals studied per group. *P < 0.05 from the corresponding value in Dusp5 KO rats vs. WT rats. #P < 0.05 from DOCA-salt treated value vs. control within strain.