TABLE 1.
Rats |
Perfusion Pressure (mm Hg) |
|||
---|---|---|---|---|
60 |
120 |
180 |
||
ID (μm) | ||||
Vessels (calcium) | ||||
Af-art | WT | 17.1 ± 0.6 | 15.3 ± 0.7 | |
Dusp5 KOa | 18.9 ± 0.4 | 13.5 ± 0.3 | ||
IA | WT | 28.8 ± 3.5 | 28.2 ± 3.7 | 28.8 ± 3.8 |
WT DOCAb | 30.4 ± 3.1 | 31.4 ± 4.2 | 36.2 ± 4.6 | |
Dusp5 KOa | 24.3 ± 1.9 | 23.1 ± 2.3 | 21.2 ± 1.6 | |
Dusp5 KO DOCAa | 31.3 ± 5.5 | 28.2 ± 4.9 | 28.7 ± 4.3 | |
Vessels (calcium Free) | Rats | |||
Af-art | WT | 17.6 ± 0.6 | 19.1 ± 0.7 | |
Dusp5 KO | 18.9 ± 0.4 | 21.4 ± 0.5 | ||
IA | WT | 48.7 ± 5.1 | 53.3 ± 4.6 | 52.6 ± 5.1 |
WT DOCA | 43.8 ± 3.8 | 45.8 ± 3.1 | 47.6 ± 4.2 | |
Dusp5 KO | 44.0 ± 3.1 | 47.3 ± 3.2 | 49.4 ± 3.2 | |
Dusp5 KO DOCA | 49.9 ± 8.2 | 54.5 ± 9.0 | 58.6 ± 10.1 |
Indicates P < 0.05 from the corresponding value in Dusp5 KO vs. WT rats.
Indicates P < 0.05 from DOCA-salt treated vs. baseline value within strain.