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. 2019 Aug;370(2):206–217. doi: 10.1124/jpet.119.258954

TABLE 1.

Inner diameters of isolated perfused afferent arteriole and interlobular artery in response to elevations in perfusion pressure

Comparison of absolute values of inner diameter of isolated perfused Af-art and IA in response to elevations in perfusion pressure. Mean values ± S.E.M. are presented.


Rats
Perfusion Pressure (mm Hg)
60
120
180
ID (μm)
Vessels (calcium)
 Af-art WT 17.1 ± 0.6 15.3 ± 0.7
Dusp5 KOa 18.9 ± 0.4 13.5 ± 0.3
 IA WT 28.8 ± 3.5 28.2 ± 3.7 28.8 ± 3.8
WT DOCAb 30.4 ± 3.1 31.4 ± 4.2 36.2 ± 4.6
Dusp5 KOa 24.3 ± 1.9 23.1 ± 2.3 21.2 ± 1.6
Dusp5 KO DOCAa 31.3 ± 5.5 28.2 ± 4.9 28.7 ± 4.3
Vessels (calcium Free) Rats
 Af-art WT 17.6 ± 0.6 19.1 ± 0.7
Dusp5 KO 18.9 ± 0.4 21.4 ± 0.5
 IA WT 48.7 ± 5.1 53.3 ± 4.6 52.6 ± 5.1
WT DOCA 43.8 ± 3.8 45.8 ± 3.1 47.6 ± 4.2
Dusp5 KO 44.0 ± 3.1 47.3 ± 3.2 49.4 ± 3.2
Dusp5 KO DOCA 49.9 ± 8.2 54.5 ± 9.0 58.6 ± 10.1
a

Indicates P < 0.05 from the corresponding value in Dusp5 KO vs. WT rats.

b

Indicates P < 0.05 from DOCA-salt treated vs. baseline value within strain.