TABLE 2.
Absolute values of renal blood flow in response to changes in renal perfusion pressure
Comparison of absolute values of RBF in response to changes in RPP. Mean values ± S.E.M. are presented.
| RPP |
RBF |
||||
|---|---|---|---|---|---|
| WT |
DUSP5 KO |
SD | |||
| Ctrl |
DOCA |
Ctrl |
DOCA |
Ctrl |
|
| mm Hg | ml/min | ||||
| 60 | 4.4 ± 0.3 | 4.6 ± 0.3 | 3.6 ± 1.3 | 5.5 ± 0.2 | 5.4 ± 0.7 |
| 80 | 6.2 ± 0.9 | 6.6 ± 1.2 | 6.4 ± 0.4 | 7.0 ± 0.5 | 6.0 ± 0.7 |
| 100 | 7.2 ± 0.6 | 7.7 ± 0.6 | 7.5 ± 0.6 | 7.7 ± 0.3 | 6.2 ± 0.6 |
| 120 | 7.6 ± 1.2 | 8.1 ± 0.2 | 7.7 ± 0.7 | 8.0 ± 1.3 | 6.2 ± 0.6 |
| 140 | 7.9 ± 1.8 | 8.7 ± 0.8 | 7.9 ± 0.4 | 8.0 ± 0.4a | 6.2 ± 0.6 |
| 160 | 8.0 ± 0.8 | 9.1 ± 1.6 | 8.3 ± 0.5 | 8.4 ± 0.7a | 6.7 ± 0.8 |
| 180 | 8.5 ± 1.1 | 10.2 ± 0.5 | 8.5 ± 0.8 | 8.7 ± 1.7a | 7.6 ± 0.5 |
a
Indicates P < 0.05 from DOCA-salt–treated vs. baseline value within strain.