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. 2019 Jul 10;10:1553. doi: 10.3389/fmicb.2019.01553

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Copyright © 2019 Migliorini, Brüggemann, de Sales, Koga, de Souza, Martino, Galhardo and Severino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Induced mutagenesis (fold-change) following treatment with sub-inhibitory concentrations of CIP for PA14-UCBPP and six clinical isolates. Sub-inhibitory concentrations of CIP were 0.03 μg/mL for HIAE_PA11 and 0.06 μg/mL for the other strains. The orange bar corresponds to the reference strain PA14-UCBPP, the yellow bars correspond to the blood culture isolates and the green bars correspond to the bronchoalveolar lavage isolates. N = 15.