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Total Gd concentration in the mouse brain based on protein molecular size at 10d after Gadopentetate (a), Gadobutrol(b) or Gadoterate(c) injection. At 10d, there is a significant reduction of Gd concentration compared to the concentration at 5 min. Almost all Gd from Gadoterate was eliminated, while some Gd from Gadopentetate and Gadobutrol was retained throughout the brain.
