Table 4.

Univariate and Multivariate Analysis of Preoperative MR Features and Laboratory Indicators for Predicting Early NCR of HCC

	Univariate analysis	Multivariate analysis
	P	β	SE	P	OR	95% CI
<2 cm
Procollagen III	0.019	0.098	0.085	0.248	1.103	0.934–1.304
Hyaluronic acid	0.080	0.001	0.001	0.442	1.101	0.998–1.004
2–5 cm
Tumor size	0.079	−0.063	0.341	0.852	0.939	0.481–1.831
Irregular margin	<0.001	1.672	0.495	0.001	5.324	2.018–14.045
Arterial peritumoral enhancement	0.041	0.324	0.594	0.585	1.383	0.432–4.426
Rim enhancement	0.013	0.733	0.519	0.158	2.081	0.752–5.757
Satellite nodules	0.031	0.681	0.692	0.326	1.975	0.508–7.671
Intratumoral artery	0.034	0.519	0.499	0.298	1.681	0.632–4.468
>5 cm
Irregular margin	<0.001	2.621	1.123	0.020	13.753	1.522–124.267
Arterial peritumoral enhancement	<0.001	1.831	0.799	0.022	6.241	1.304–29.864
Satellite nodules	0.089	0.349	0.630	0.579	1.418	0.413–4.870
PV/HV invasion	0.005	0.370	0.807	0.646	1.448	0.298–7.043
Intratumoral artery	0.009	−0.149	0.941	0.875	0.862	0.136–5.453
Radiological capsule	0.074	0.100	0.547	0.854	1.106	0.378–3.233
Minimum distance	0.084	−0.277	0.222	0.211	0.758	0.491–1.170
alpha-fetoprotein	0.020	1.576	0.773	0.042	4.838	1.062–22.028

Notes Variables with a P value < 0.1 according to the univariate analysis were entered into the multivariate analysis.

Minimum distance is defined as the minimum distance between the liver envelope and the edge of the tumor.

β, partial regression coefficient; SE, Standard Error; OR, odds ratio; CI, confidence interval; PV/HV, portal vein/hepatic vein.