Figure 1.

AHNAK was predicted to be a driver gene in PDAC. A: AHNAK was predicted as a driver gene in PDAC as analyzed using the IntOGen website. B and C: Nineteen images of PDAC and adjacent non-tumor tissues were downloaded from the Protein Atlas database, which showed high AHNAK protein expression in PDAC compared to adjacent non-tumor tissues. D and E: Twenty-two pairs of PDAC sequencing data were downloaded from the GEO database, which showed upregulated AHNAK mRNA expression in PDAC. F and G: PDAC data were downloaded from TCGA database. The Kaplan-Meier analysis showed that high AHNAK expression was associated with shortened DFS and poor OS. H and I: multivariate analysis showed that AHNAK and the AJCC N stage were independent prognostic predictors of DFS, but not an independent prognostic predictor of OS in PDAC.