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. 2019 Jul 11;11:6411–6424. doi: 10.2147/CMAR.S197607

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© 2019 He et al.

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Loss of STC2 promotes radiation-triggered cell cycle alteration.

Notes: (A) Cells were cultured under either normoxic or hypoxic conditions to 80% confluence. Then, cells were exposed to 4 Gy of X-radiation and cultured for another 6 hrs. The cells were trypsinized and cell cycle distribution was determined by PI staining and flow cytometric analysis of DNA contents. (B, C) Results from triplicate experiments as shown in panel A were quantified, and the percentages of cells in the G₀/G₁, S and G₂/M phases were presented as means±SD. *P<0.05; **P<0.01; ***P<0.001.