Table 8.
Blood chemistry | Model | Mean at screening | Summary statistic | β | p | p* |
---|---|---|---|---|---|---|
CEA | Change vs. Dosage Ratio | 35.54 (ng/mL) | Change = 15.67 | −202.15 | 0.046 | 0.61 |
Alkaline Phosphatase | Difference vs. Dosage | 158.21 (U/L) | Difference = 22.35 | −3.02 | 0.012 | 0.065 |
SGOT/AST | Difference vs. Dosage Ratio | 41.5 (U/L) | Difference = 5.25 | −0.748 | 0.018 | 0.30 |
Total Bilirubin | Difference vs. Dosage | 0.6 (mg/dL) | Difference = 0.18 | −0.01 | 0.006 | 0.048 |
Potassium | Difference vs. Dosage | 4.62 (mmol/L) | Difference = −0.37 | −0.028 | 0.039 | 0.17 |
β is the estimated regression coefficient, p-values are based on a t-test of the deviation of β from 0.
Change = Last Treatment – First Screening.
Difference = Mean Treatment – Mean Screening.